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Global Cell & Gene Therapy Business and Investment Opportunities

According to BioIntel360, the global cell and gene therapy market size is expected to record a CAGR of 26.2% during 2023-2027 to reach US$53,950.5 million by 2027, increasing from US$21,293.4 million...

Global Cell & Gene Therapy Business and Investment Opportunities – Analysis & Market Size by Technology, Clinical Trials, Patents, Financial Deals, Competitive Landscape – Q1 2023 Update
Summary
According to BioIntel360, the global cell and gene therapy market size is expected to record a CAGR of 26.2% during 2023-2027 to reach US$53,950.5 million by 2027, increasing from US$21,293.4 million in 2023. Over the last five years, the sector has recorded a CAGR of 28.0% to reach US$16,734.3 million in 2022.

The lives of people all over the world have been improved by traditional methods of patient treatment that use drugs and surgery, yet there are many diseases possibly even most of them for which these conventional methods only slow the progression of the illness without curing it. This flaw is especially evident when treating monogenic diseases, which are congenital illnesses brought on by single-gene abnormalities. 

More than 30 million people in the United States are thought to be affected by one of the more than 7,000 rare diseases that exist. Cells and genetically modified cells are "living drugs" that may repair and replace damaged tissues or ill organs, which makes them fundamentally different from medications and surgery. Due to these characteristics, they may be used to treat a variety of conditions.

There are presently six FDA-approved CAR-T cell therapies available to patients in the United States and Europe to treat different types of blood cancers. These are quite promising therapies that are being developed for both rare and common disorders.

A glimmer of hope for patients waiting for long-term, potentially curative treatments is the fact that more than 1,000 clinical trials, including 200 in Phase III, are now under progress. Phase I/II combo studies are frequently used. Because it enables sponsors to improve and accelerate their clinical development programmes, this design approach is still being used more and more in the industry. The industry must overcome funding, regulatory, and legislative barriers, and many patients won't benefit unless we transform the way we provide healthcare.

An expansion of the CGT pipeline expects increased global cell and gene therapy market growth
The year 2022 marked a turning point for the licencing of never-before-approved gene treatments, with three new medications licenced to treat uncommon illnesses and another authorised to treat bladder cancer. This is just the first wave of the transforming ripple. By the end of 2023, innovative cell or gene therapies may have received approval for use in Europe, the United States, or both. The industry is on the verge of achieving the FDA's widely reported 2019 forecast that 10–20 innovative cell and gene therapies will be approved annually by 2025.

• In December 2022 a chimeric antigen receptor (CAR) T-cell therapy called Yescarta (axicabtagene ciloleucel) has been approved by the Japanese Ministry of Health, Labour and Welfare (MHLW) for the initial treatment of patients with relapsed/refractory large B-cell lymphoma (R/R LBCL), including those with diffuse large B-cell lymphoma and primary mediastinal large B-cell lymphoma, transformed follicular lymphoma, and high-grade B-cell lymphoma.  

• Yescarta® (axicabtagene ciloleucel), a CAR T-cell treatment, was given FDA approval in April 2022 for treating adult patients with large B-cell lymphoma.
• The European Commission (EC) approved Kymriah® (tisagenlecleucel), a CAR-T cell therapy, for the treatment of adult patients with relapsed or refractory (r/r) follicular lymphoma (FL) after two or more lines of systemic therapy, according to Novartis.

• Commercial demand for Abecma (idecabtagene vicleucel) remained strong into 2022. In addition to increasing manufacturing capacity, 2seventy bio and BMS made major advancements in key supply chain indicators.

• In 2023, the company projects topline U.S. sales of $470-$570M thanks to further expansions in the manufacturing capacity of vector and pharmacological products, including an extra adherent vector manufacturing suite. 2seventy Bio anticipates additional commercial growth with an anticipated label expansion in 2024–2025. With this expansion, 2seventybio anticipates that Abecma will produce $200-300M in operational income for 2seventybio between 2024 and 2025.

• The first cell-based gene therapy, Zynteglo (betibeglogene autotemcel), has been given the green light by the US Food and Drug Administration to treat adult and paediatric beta-thalassemia patients who need regular red blood cell transfusions

In the future, it's anticipated that M&A activity will increase in cell and gene therapy market
• In the field of CGT, where licencing and cooperative arrangements continue to dominate. This is hardly surprising given the relative youth of CGT technology, as there are still questions about values and technical obstacles. Partnerships give the licensor or investor a reduced risk way to increase CGT offerings without taking on full financial responsibility or experiencing the productivity disruption frequently associated with M&A.

• Investments are going into firms of all stages of development, from start-ups to significant acquisitions by big pharmaceutical firms. In 2019, to purchase Celgene, Bristol Myers Squibb paid $74 billion. The largest of them are involved in oncology treatments. 

• Cell and gene therapy market draws an increased amount and share of public and private investment despite the limited number of licenced products. Despite the fact that during the past ten years, all private sector investment in the life sciences has increased significantly, the exponential growth of overall investments in cell and gene therapy firms is extraordinary.

• Neogene Therapeutics, a global clinical-stage biotechnology firm that is leading the discovery, development, and production of next-generation T-cell receptor treatments (TCR-Ts), which provide a unique cell therapy strategy for treating cancer, has announced that AstraZeneca is acquiring it.

Growing cell and gene therapy enterprises have received support from this surge in private money as they reach the stock market. Initially, it showed early growth but later it went through a period of severe distortions during the pandemic. It is expected that cell and gene firms return to a more measured growth trajectory, underpinned by a growing number of clinical milestones and perhaps more regulatory approvals, as stock markets adapt and the economy picks up through the projected period.

European region may regain its feet in the field of cell and gene therapy with regulatory checks
• Although authorities in the US and Europe are moving forward with reforming their regulatory frameworks in response to scientific advancements, barriers to patient access remain a major issue in both places. 

• The European Union will update its pharmaceuticals legislation; the proposal is anticipated in the first quarter of 2023. The project will have a significant impact on whether European patients have access to advanced therapy medicinal products for years to come by balancing affordability and access, among other issues.

• Europe faces tremendous challenges, particularly when it comes to access. Having the European Medicines Agency, a top-notch regulatory organisation, and having approved the first gene therapy, Europe has been a tremendous pioneer in the sector in many ways. However, due to a combination of complex factors, Europe is already lagging on certain crucial fronts.

Regulatory trends that will shape the future of the cell and gene therapy market 
• In the upcoming years, it is anticipated that filing application numbers would rise. The amount of requests for Breakthrough (BT) and Regenerative Medicine Advanced Therapy (RMAT) designations, which are submitted concurrently with or during an ongoing IND file, has recently increased. While the benefits of BT and RMAT designations are comparable to those of fast-track designation, these designations also call for more robust supporting documentation.

• Within the framework of the NIH Accelerating Medicines Partnership Program, the FDA recently launched a new effort. The Bespoke Gene Therapy Consortium (BGTC) was established to remove significant barriers and streamline the small-batch gene therapy research process. By giving details on basic and clinical research, manufacturing, production, and regulatory needs, the BGTC will serve as a traffic light for these therapies.

• The FDA's "INTERACT" casual meeting programme is a relatively new project. This initiative involves informal talks between the Center for Biologics Evaluation and Research (CBER) employees and researchers/sponsors who are in the pre-IND stage of development to address the concerns and demands faced by the CGT industry within current clinical guidelines. The INTERACT meetings do not charge anything under the Prescription Drug User Fee Act (PDUFA). They are given based on CBER's resources and availability, and they do not take the place of other official meetings. Therefore, it is advised to ask for a pre-IND meeting before submitting an IND to start the Phase I first-in-human investigation. This is crucial when looking for advice on the designs of toxicity study plans.

• The FDA has just launched the Gene Therapy Pilot Program, which entails giving sponsors input in real-time throughout the clinical development process. The development cycle and submission review time should be sped up by the combination of new meeting formats. Together, these programmes provide opportunities for sponsors and regulators to speak and debate technical advancements more frequently.

To ensure that patients benefit from this technology, however, there are crucial challenges that exist within the cell and gene therapy market and they must be resolved. Industry and the healthcare sector are prepared to invest in the CGT ecosystem and have faith that long-term problems (such as costs, safety, and reimbursement) will be resolved.

Firms in the cell and gene therapy market and their investors should understand and distinguish marketing hype from legitimate science. This is a new market with enormous potential opportunities, but it still carries many risks until it is economically established. The potential of CGT to usher in a new era of medicine has undoubtedly inspired a lot of optimism globally

This report presents an in-depth analysis of the current cell and gene therapy market scenario, with an emphasis on the future trajectory of potential opportunities in the cell and gene therapy industry. In addition to a combination of exhaustive secondary research along with primary research, BioIntel360’s research methodology leverages a proprietary predictive analytics platform to provide unbiased business intelligence and answer key questions related to the cell and gene therapy market forecast.

It provides a detailed analysis of cell and gene therapy market dynamics, covering clinical trials, patent data, financial deals, and company profiling details. It details market opportunities and risks across key segments – by type of therapy segment, by the purpose of manufacturing, by type of cell, by product, by route of administration, delivery mode, source of cell, source of manufacturing, therapeutic class, technology, and by type of therapy. It also details market dynamics across various end-use sectors to assess emerging opportunities.

In addition, this report provides analyst commentary on key trends, drivers, strategies, innovations, and regulations in the cell and gene therapy market.

This title from BioIntel360 provides global and regional insights along with data-centric analysis for the following 6 regions and 20 countries:

• Global
• North America
o United States
o Canada
o Mexico

• Europe
o United Kingdom
o France
o Germany
o Italy
o Netherlands

• Asia-Pacific
o China
o Japan
o Australia
o India
o South Korea

• Latin America
o Brazil
o Argentina
o Colombia

• MEA
o Israel
o South Africa
o UAE
o Saudi Arabia

Scope
Insights and data in the report have been segmented under the following six modules:

Module 1: Global Cell and Gene Therapy Funding and Investments Outlook
This module provides insights and data related to cell and gene therapy partnerships and investment (research and development, mergers and acquisitions, product development, commercialization, licensing, and manufacturing) and allows a peek into the futuristic trends of cell and gene therapy technology investment area. 

Module 2: Global Cell and Gene Therapy Clinical Trial Data Assessment
This module evaluates the data available from clinical trials conducted in this sector, representing a bird’s eye view of emerging market dynamics and risks in the cell and gene therapy sector.

Module 3: Global Cell and Gene Therapy Patent Data Analysis
This module presents an exhaustive study of cell and gene therapy patent analytics at various levels, including strategic research planning as well as analyzing their potential applications.

Module 4: Competitive Landscape
This module provides detailed information along with a scoring matrix of key companies related to the cell and gene therapy industry, including their historical performance and the latest developments.

Module 5: Global Cell and Gene Therapy Market Size and Forecast
This module provides projections on the market's development during the years 2018-2027 after the profound evaluation of market dynamics at the deeper segmentation level. This report also provides an in-depth, data-centric analysis of the global cell and gene therapy market at regional and country levels:

Cell & Gene Therapy Market Size by Different Therapy Segment, 2018-2027
• Cell and Gene Modified Cell Therapies
• Gene Therapy and Genome Therapy
• DNA & RNA Therapeutics

Cell & Gene Therapy Market Size by Purpose of Manufacturing
• Commercial
• Clinical

Cell & Gene Therapy Market Size by Product
• Abecma
• Amondys
• Breyanzi
• Carvykti
• Givlaari
• Kimmtrak
• Kymriah
• Leqvio
• Luxturna
• Onpattro
• Oxlumo
• Rethymic
• Skysona
• Stratagraft
• Tecartus
• Tegsedi
• Viltepso
• Vyondys
• Yescarta
• Zolgensma
• Zynteglo

Cell & Gene Therapy Market Size by Route of Administration
• Injectables
• Infusions
• Bioscaffolds
• Topicals

Cell & Gene Therapy Market Size by Type of Cell
• CAR-T Cell
• TCR Cell

Cell & Gene Therapy Market Size by  Type of Therapy
• T-Cell Therapies
• NK Cell
• Dendritic Cell Therapies
• Stem Cell Therapies

Cell & Gene Therapy Market Size by  Source of Cell
• Autologous
• Allogenic

Cell & Gene Therapy Market Size by  Delivery Mode
• In vivo
• ex-vivo

Cell & Gene Therapy Market Size by  Source of Manufacturing
• In-House
• Contract Manufacturing

Cell & Gene Therapy Market Size by Therapeutic Class
• Oncology
• Neurology
• Ophthalmology
• Musculoskeletal
• Others

Cell & Gene Therapy Market Size by  Technology
• Viral Vector Technology
• Cell Immortalization Technology
• Genome Editing Technology
• Others

Cell & Gene Therapy Market Size by  End User
• Pharmaceutical & Biotechnology Companies
• Academic & Research Institutes
• Hospital & Clinics

Cell & Gene Therapy Market Size by  Regions

• North America
- U. S.
- Canada
- Mexico

• Europe
- France
- United Kingdom
- Germany
- Italy
- Netherlands

• Asia-Pacific
- China
- Japan
- Australia
- India
- South Korea

• MEA region
- Israel
- South Africa
- U.A. E
- Saudi Arabia

• Latin America
- Brazil
- Argentina
- Colombia

Key Companies Covered
• Gilead Company
• Novartis 
• Roche Holding AG
• Johnson & Johnson
• Bristol Myers Squibb
• bluebird bio
• Alnylam Pharmaceuticals

Module 6 Regulatory Outlook
This module contains a detailed understanding of the ethical, legal, and social implications of cell and gene therapy technology.
Reason to buy
• Cell & Gene Therapy Market Dynamics: Understand market opportunities and key trends along with forecast (2023-2027). Understand market dynamics across various segments such as by type of therapy, the purpose of manufacturing, type of cell, product, route of administration, delivery mode, source of cell,  source of manufacturing, therapeutic class, technology, end-user, by-products, delivery, geographical region, and company profiling.  

• Competitive Landscape Analysis: Market position and snapshot of key players in the development of cell and gene therapies. Each profile includes a brief overview of the company, information on its therapeutic pipeline, financial data (where available), the most recent events, and future direction of the market. 

• Clinical Trial Analysis: Insights into opportunities across cell and gene-based therapies that have been completed or are still ongoing, using parameters such as trial status, trial registration year, an indication of the target disease, trial phase, patient enrolment, and sponsor/collaborator type. 

• Develop Market-Specific Strategies: Identify growth segments based on a thorough analysis of the cell & gene therapy patents that have been applied for or granted based on the patent type, the issuing agency, and patent offices involved, the Cooperative Patent Classification (CPC) symbols, the firm type, significant industry and non-industry participants (based on many patents), and discrete patent assignees.

• Financial Deals Insights: Get insights into various cell and gene therapy partnerships that have been developed, including those for research and development (R&D), clinical trials, mergers and acquisitions, product development, commercialization, licencing, and manufacturing. A complete analysis of the various investments made in companies that specialise in developing drugs using cell and gene therapy technologies.
Table of Contents
 This market intelligence report features an in-depth analysis on the current market dynamics of cell and gene therapy market. 

It provides a detailed analysis of cell and gene therapy market dynamics, covering clinical trials, patent data, financial deals, and competitive landscape through 38 sections, 1048 tables, and 1513 charts.

Chapter 1 About this Report

1.1 Research Methodology
1.2 Definitions
1.3 Disclaimer

Chapter 2 Global Cell and Gene Therapy Market Outlook and Future Growth Dynamics

2.1 Introduction
2.2 Market Opportunities and Growth Dynamics
2.3 Strategy and Innovations
2.4 Regulation and Challenges Related to Cell and Gene Therapy Around the Globe

Chapter 3 Regulatory Dynamics Assessment Across Different regions

3.1 North America Cell and Gene Therapy Regulations
3.2 Europe Cell and Gene Therapy Regulations
3.3 Asia Pacific Cell and Gene Therapy Regulations
3.4 Latin America Cell and Gene Therapy Regulations
3.5 Middle East & Africa region Cell and Gene Therapy Regulation

Chapter 4 Global Cell and Gene Therapy Discovery and Clinical Pipeline Market Attractiveness

4.1 Cell and Gene Therapy Based: Discovery and Clinical Pipeline, 2023
4.2 Cell and Gene Therapy Based: Discovery and Clinical Pipeline, 2024
4.3 Cell and Gene Therapy Based: Discovery and Clinical Pipeline, 2025-2027
4.4 Approved Cell and Gene Therapies, 2017-2022
4.5 Anticipated Regulatory Decisions, 2023
4.6 Predicted Cell and Gene Therapy Product Launches, 2018-2030
4.7 List of Top 10 Innovation Driving Worldwide CGT Sales in 2022
4.8 FDA Approved Cell and Gene Therapies

Chapter 5 Global Cell and Gene Therapy Financial Deals & Alliances Market Dynamics & Outlook

5.1 Cell and Gene Therapy Financial Deals & Alliances Market Prediction and Estimation
5.2 Cell and Gene Therapy Financial Deals Vs Mergers & Acquisition, 2022 vs 2025
5.3 Cell and Gene Therapy Financial Deals Analysis by Different Therapy Segment, 2022 vs 2025
5.4 Cell and Gene Therapy Financial Deals Analysis by Type of Cell, 2022 vs 2025
5.5 Cell and Gene Therapy Financial Deals Analysis by Therapeutic Class, 2021 vs 2022
5.6 Cell and Gene Therapy Financial Deals Analysis by Therapeutic Class Prediction, 2022 vs 2025
5.7 Cell and Gene Therapy Financial Deals Analysis by Phase-Wise Deals, 2022 vs 2025
5.8 Cell and Gene Therapy Financial Deals Analysis by Type of Diseases, 2022 vs 2025
5.9 Cell and Gene Therapy Financial Deals Analysis by Type of Industry, 2022 vs 2025
5.10 Cell and Gene Therapy Financial Deals Analysis by Region, 2022 vs 2025
5.11 Cell and Gene Therapy Financial Deals Total Upfront Cash and Equity, 2018-2022
5.12 Number of Cell and Gene Therapy in Clinical Stage, 2018-2022
5.13 Recent Deals and Partnership of Cell and Gene Therapy
5.14 Recent Cell and Gene Therapy Mergers and Acquisitions
5.15 Global Cell and Gene Therapy Deals Landscape, 2020-2022
5.16 Cell and Gene Therapy Financial Deals Analysis by Funding and Investment

Chapter 6 Global Cell and Gene Therapy Patent Analysis & Outlook

6.1 Cell and Gene Therapy Historical and Futuristic Trend of Patent, 2018-2027
6.2 Cell and Gene Therapy Patent Analysis by Type of Cell Therapy Players, 2022 vs 2025
6.3 Cell and Gene Therapy Patent Analysis by Type of Gene Therapy Player, 2022 vs 2025
6.4 Cell and Gene Therapy Patent Analysis by Cell Type, 2022 vs 2025
6.5 Cell and Gene Therapy Patent Analysis by Product
6.6 Cell Therapy Patent Analysis by Patent Type, 2018-2022
6.7 Gene Therapy Patent Analysis by Patent Type, 2018-2022
6.8 Cell Therapy Patent Analysis by Legal Status, 2018-2022
6.9 Gene Therapy Patent Analysis by Legal Status, 2018-2022
6.1 Cell Therapy Patent Analysis by Top Patent Owners
6.11 Gene Therapy Patent Analysis by Top Patent Owners
6.12 Cell Therapy Patent Analysis by Top Patent Applicants
6.13 Gene Therapy Patent Analysis by Top Patent Applicants
6.14 Cell and Gene Therapy: Cell Therapy Top Patent Applicants Benchmarking Analysis
6.15 Cell and Gene Therapy: Gene Therapy Key Patent Applicant Benchmarking Analysis
6.16 Cell Therapy Patent Analysis by Published Status
6.17 Gene Therapy Patent Analysis by Published Status
6.18 Cell Therapy Patent Analysis by Investors
6.19 Gene Therapy Patent Analysis by Investors
6.20 Cell Patent Analysis by CPC Classification Code
6.21 Gene Therapy Patent Analysis by CPC Classification Code
6.22 Cell Therapy Patent Documents by Jurisdiction
6.23 Gene Therapy Patent Documents by Jurisdiction
6.24 List of Recent Cell Therapy Patents
6.25 List of Recent Gene Therapy Patents

Chapter 7 Cell and Gene Therapy Clinical Trial Analysis & Outlook

7.1 Cell and Gene Therapy Clinical Trial Historical and Futuristic Trend
7.2 Cell and Gene Therapy Clinical Trial Region-wise Prediction & Estimation, 2018-2027
7.3 Cell Therapy Clinical Trial Analysis by Country-wise Analysis
7.4 Gene Therapy Clinical Trial Analysis by Country-wise
7.5 Cell and Gene Therapy Clinical Trial Analysis by Age Group
7.6 Cell and Gene Therapy Clinical Trial Analysis by Funding Agency
7.7 Cell and Gene Therapy Clinical Trial Analysis by Documents
7.8 Cell and Gene Therapy Clinical Trial Analysis by Therapeutic Class
7.9 Cell and Gene Therapy Clinical Trial Analysis by Phase-wise
7.10 Cell and Gene Therapy Clinical Trial Analysis by Status
7.11 Number of Cell and Gene Therapy Assets in Clinical Pipeline
7.12 Cell and Gene Therapy Clinical Trial Analysis by Type of Diseases
7.13 Cell and Gene Therapy Clinical Trial Analysis by Study Type

Chapter 8 Cell and Gene Therapy Competitive Landscape Analysis: Key Company Profiles and Strategic Initiatives

8.1 Cell and Gene Therapy Competitive Index Ranking & Attractiveness Quadrant
8.2 Cell and Gene Therapy Company Market Share
8.3 Cell and Gene Therapy Competitive Mapping Quadrant
8.4 Cell and Gene Therapy Competitive Landscape by End Markets
8.5 Key Companies by Regions
8.6 Competitive Landscape by Different Therapy Segment of Cell and Gene Therapy
8.7 Gene Therapy Public Company Competitive Landscape
8.8 Cell Therapy Public Company Competitive Landscape
8.9 Cell and Gene Therapy Developers Worldwide
8.10 Gilead Sciences
8.11 Novartis
8.12 Johnson & Johnson
8.13 Bristol Myers Squibb
8.14 Roche Holding AG
8.15 bluebird bio
8.16 Alnylam Pharmaceuticals

Chapter 9 Global Cell and Gene Therapy Market Size and Forecast, 2018-2027

9.1 Cell and Gene Therapy Market Share by Different Therapy Segment, 2018-2027
9.1.1 Market Size by Cell and Gene Modified Cell Therapies, 2018-2027
9.1.2 Market Size by Gene Therapy and Genome Therapy, 2018-2027
9.1.3 Cell and Gene Therapy Market Size by DNA & RNA Therapeutics, 2018-2027 

9.2 Cell and Gene Therapy Market Share by Purpose of Manufacturing, 2018-2027
9.2.1 Cell and Gene Therapy Market Size by Commercial, 2018-2027
9.2.2 Cell and Gene Therapy Market Size by Clinical, 2018-2027

9.3 Cell and Gene Therapy Market Share by Product, 2018-2027

9.4 Cell and Gene Therapy Market Share by Route of Administration, 2018-2027
9.4.1 Cell and Gene Therapy Market Size by Injectables, 2018-2027
9.4.2 Cell and Gene Therapy Market Size by Topicals, 2018-2027
9.4.3 Cell and Gene Therapy Market Size by Infusions, 2018-2027
9.4.4 Cell and Gene Therapy Market Size by Bioscaffolds, 2018-2027

9.5 Cell and Gene Therapy Market Share by Type of Diseases, 2018-2027
9.5.1 Cell and Gene Therapy Market Size by Rare Diseases, 2018-2027
9.5.2 Cell and Gene Therapy Market Size by Non-Rare Diseases, 2018-2027

9.6 Cell and Gene Therapy Market Share by Type of Cell, 2018-2027
9.6.1 Cell and Gene Therapy Market Size by CAR-T Cell, 2018-2027
9.6.2 Cell and Gene Therapy Market Size by TCR Cell, 2018-2027

9.7 Cell and Gene Therapy Market Share by Therapy, 2018-2027
9.7.1 Cell and Gene Therapy Market Size by T-Cell Therapies, 2018-2027
9.7.2 Cell and Gene Therapy Market Size by NK Cell, 2018-2027
9.7.3 Cell and Gene Therapy Market Size by Dendritic Cell Therapies, 2018-2027
9.7.4 Cell and Gene Therapy Market Size by Stem Cell Therapies, 2018-2027

9.8 Cell and Gene Therapy Market Share by Source of Cell, 2018-2027
9.8.1 Cell and Gene Therapy Market Size by Autologous, 2018-2027
9.8.2 Cell and Gene Therapy Market Size by Allogenic, 2018-2027

9.9 Cell and Gene Therapy Market Share by Delivery Mode, 2018-2027
9.9.1 Cell and Gene Therapy Market Size by In-vivo, 2018-2027
9.9.2 Cell and Gene Therapy Market Size by Ex-vivo, 2018-2027

9.10 Cell and Gene Therapy Market Share by Source of Manufacturing, 2018-2027
9.10.1 Cell and Gene Therapy Market Size by In-House, 2018-2027
9.10.2 Cell and Gene Therapy Market Size by Contract Manufacturing, 2018-2027

9.11 Cell and Gene Therapy Market Share by Therapeutic Class, 2018-2027
9.11.1 Cell and Gene Therapy Market Size by Oncology, 2018-2027
9.11.2 Cell and Gene Therapy Market Size by Neurology, 2018-2027
9.11.3 Cell and Gene Therapy Market Size by Ophthalmology, 2018-2027
9.11.4 Cell and Gene Therapy Market Size by Musculoskeletal, 2018-2027
9.11.5 Cell and Gene Therapy Market Size by Others, 2018-2027

9.12 Cell and Gene Therapy Market Share by Technology, 2018-2027
9.12.1 Cell and Gene Therapy Market Size by Viral Vector Technology, 2018-2027
9.12.2 Cell and Gene Therapy Market Size by Cell Immortalization Technology, 2018-2027
9.12.3 Cell and Gene Therapy Market Size by Genome Editing Technology, 2018-2027
9.12.4 Cell and Gene Therapy Market Size by Others Technologies, 2018-2027

9.13 Cell and Gene Therapy Market Share by End User, 2018-2027
9.13.1 Cell and Gene Therapy Market Size by Pharmaceutical & Biotechnology Companies, 2018-2027
9.13.2 Cell and Gene Therapy Market Size by Academic & Research Institutes, 2018-2027
9.13.3 Cell and Gene Therapy Market Size by Hospital & Clinics, 2018-2027

Chapter 9 - Chapter 38: This section contains chapters providing cell and gene therapy market sizing and forecast for additional 20 countries and 6 regions.


List Of Table
This report includes 1048 tables across various sections covering global, regional, and country level analysis. Due to space constraints, limited number of tables have been displayed here.

Table 1: Cell and Gene Therapy Financial Deals Market Size and Forecast, by Value (USD Million), 2018-2027 
Table 2: Cell and Gene Therapy Financial Deals Market Size and Forecast, by Volume, 2018-2027 
Table 3: Cell and Gene Therapy Fundings and Investment Market Size and Forecast, by Value (USD Million), 2018-2027 
Table 4: Cell and Gene Therapy Fundings and Investment Market Size and Forecast, by Volume, 2018-2027 
Table 5: Global Cell and Gene Therapy Market Size by Value (USD MM) 2018-2027 
Table 5: Global Cell and Gene Therapy Market Size by Cell and Gene Modified Cell Therapies, by Value (USD MM), 2018-2027 
Table 6: Global Cell and Gene Therapy Market Size by Gene Therapy and Genome Therapy, by Value (USD MM) 2018-2027 
Table 7: Global Cell and Gene Therapy Market Size by DNA & RNA Therapeutics, by Value (USD MM) 2018-2027 
Table 8: Global Cell and Gene Therapy Market Size by Commercial, by Value (USD MM) 2018-2027 
Table 9: Global Cell and Gene Therapy Market Size by Clinical, by Value (USD MM) 2018-2027 
Table 10: Global Cell and Gene Therapy Market Size by Injectables, by Value (USD MM) 2018-2027 
Table 11: Global Cell and Gene Therapy Market Size by Topicals, by Value (USD MM) 2018-2027 
Table 12: Global Cell and Gene Therapy Market Size by Infusions, by Value (USD MM) 2018-2027 
Table 13: Global Cell and Gene Therapy Market Size by Bio scaffolds, by Value (USD MM) 2018-2027 
Table 14: Global Cell and Gene Therapy Market Size by Rare Diseases, by Value (UDS MM) 2018-2027 
Table 15: Global Cell and Gene Therapy Market Size by Non-Rare Diseases, by Value (UDS MM) 2018-2027 
Table 16: Global Cell and Gene Therapy Market Size by CAR-T Cell, by Value (UDS MM) 2018-2027 
Table 17: Global Cell and Gene Therapy Market Size by TCR Cell, by Value (UDS MM) 2018-2027 
Table 18: Global Cell and Gene Therapy Market Size by T-Cell Therapies, by Value (USD MM), 2018-2027 
Table 19: Global Cell and Gene Therapy Market Size by NK Cell, by Value (USD MM), 2018-2027 
Table 20: Global Cell and Gene Therapy Market Size by Dendritic Cell Therapies, by Value (USD MM), 2018-2027 
Table 21: Global Cell and Gene Therapy Market Size by Stem Cell Therapies, by Value (USD MM), 2018-2027 
Table 22: Global Cell and Gene Therapy Market Size by Autologous (USD MM), 2018-2027 
Table 23: Global Cell and Gene Therapy Market Size by Allogenic (USD MM), 2018-2027 
Table 24: Global Cell and Gene Therapy Market Size by In-vivo, by Value (USD MM), 2018-2027 
Table 25: Global Cell and Gene Therapy Market Size by Ex-vivo, by Value (USD MM), 2018-2027 
Table 26: Global Cell and Gene Therapy Market Size by In-House, by Value (USD MM), 2018-2027 
Table 27: Global Cell and Gene Therapy Market Size by Contract Manufacturing, by Value (USD MM), 2018-2027 
Table 28: Global Cell and Gene Therapy Market Size by Oncology, by Value (USD MM), 2018-2027 
Table 29: Global Cell and Gene Therapy Market Size by Neurology, by Value (USD MM), 2018-2027 
Table 30: Global Cell and Gene Therapy Market Size by Ophthalmology, by Value (USD MM), 2018-2027 
Table 31: Global Cell and Gene Therapy Market Size by Musculoskeletal, by Value (USD MM), 2018-2027 
Table 32: Global Cell and Gene Therapy Market Size by Others, by Value (USD MM), 2018-2027 
Table 33: Global Cell and Gene Therapy Market Size by Viral Vector Technology, by Value (USD MM), 2018-2027 
Table 34: Global Cell and Gene Therapy Market Size by Cell Immortalization Technology, by Value (USD MM), 2018-2027 
Table 35: Global Cell and Gene Therapy Market Size by Genome Editing Technology, by Value (USD MM), 2018-2027 
Table 36: Global Cell and Gene Therapy Market Size by Others Technologies, by Value (USD MM), 2018-2027 
Table 37: Global Cell and Gene Therapy Market Size by Pharmaceutical & Biotechnology Companies, by Value (USD MM), 2018-2027 
Table 38: Global Cell and Gene Therapy Market Size by Academic & Research Institutes, by Value (USD MM), 2018-2027 
Table 39: Global Cell and Gene Therapy Market Size by Hospital & Clinics, by Value (USD MM), 2018-2027 
List of figures
This report includes 1513 figures across various sections covering global, regional, and country-level analysis. Due to space constraints, the limited number of figures have been displayed here.

Figure 1: BioIntel360 Research Methodology 
Figure 2: Cell and Gene Therapy Important Historical Events 
Figure 3: Cell and Gene Therapy Readiness Scorecard for Selected Countries 
Figure 4: Important Historical Events in Cell and Gene Therapy 
Figure 5: List of Cell and Gene Therapy Projected Launch Year, 2023 
Figure 6: List of Cell and Gene Therapy Projected Launch Year, 2024 
Figure 7: List of Cell and Gene Therapy Projected Launch Year, 2025-2027 
Figure 8: List of Approved Cell and Gene Therapies, 2017-2022 
Figure 9: United States and European Union Anticipated Regulatory Decisions, 2023 
Figure 10: List of Top 10 Innovations in Pipeline Expected to Drive Worldwide CGT Sales, 2022-2028 
Figure 11: List of Top 10 Innovations Driving Worldwide CGT Sales in 2022 
Figure 12: List of FDA Approved Cell and Gene Therapies 2017-2022 
Figure 13: Cell and Gene Therapy Financial Deals & Alliances Market Size and Forecast, by Value (USD Million), 2018-2027 
Figure 14: Cell and Gene Therapy Financial Deals & Alliances Market Share and Forecast, by Volume (%), 2018-2027 
Figure 15: Global Cell and Gene Therapy: Financial Deals Vs Mergers & Acquisition Analysis, 2022 vs 2025 
Figure 16: Global Cell and Gene Therapy Financial Deals: Analysis by Different Therapy Segment, 2022 vs 2025 
Figure 17: Global Cell and Gene Therapy Financial Deals: Analysis by Type of Cell, 2022 vs 2025 
Figure 18: Global Cell and Gene Therapy Financial Deals: Analysis by Therapeutic Class, 2021 vs 2022 
Figure 19: Global Cell and Gene Therapy Financial Deals: Analysis by Therapeutic Class, 2022 vs 2025 
Figure 20: Global Cell and Gene Therapy Financial Deals: Analysis by Phase-Wise Deals, 2022 vs 2025 
Figure 21: Global Cell and Gene Therapy Financial Deals: Analysis by Type of Diseases, 2022 vs 2025 
Figure 22: Global Cell and Gene Therapy Financial Deals: Analysis by Type of Industry, 2022 vs 2025 
Figure 23: Global Cell and Gene Therapy Financial Deals: Analysis by Region, 2022 vs 2025 
Figure 24: Cell and Gene Therapy Financial Deals Total Upfront Cash and Equity, 2018-2022 
Figure 25: Cell and Gene Therapy Financial Deals Total Upfront Cash and Equity, 2018-2022 
Figure 26: Recent Deals and Partnership of Cell and Gene Therapy 
Figure 27: Recent Cell and Gene Therapy Mergers and Acquisitions 
Figure 28: Global Cell and Gene Therapy Deals (> USD 1 Billion) Landscape, 2020-2022 
Figure 29: Cell and Gene Therapy Fundings and Investment Market Size and Forecast, by Value (USD Million), 2018-2027 
Figure 30: Cell and Gene Therapy Fundings and Investment Market Share and Forecast, by Volume (%), 2018-2027 
Figure 31: Global Cell and Gene Therapy Fundings and Investment: Analysis by Region, 2018-2022 
Figure 32: Global Cell and Gene Therapy Fundings and Investment: Analysis by Type of Industry, 2018-2022 
Figure 33: Global Cell and Gene Therapy Fundings and Investment: Analysis by Therapeutic Class, 2018-2022 
Figure 34: Global Cell and Gene Therapy Fundings and Investment: Analysis by Type, 2018-2022 
Figure 35: Global Cell and Gene Therapy Fundings and Investment: Analysis by Funding Type, 2018-2022 
Figure 36: Global Cell and Gene Therapy Fundings and Investment: Analysis by Funding Stage, 2018-2022 
Figure 37: Cell and Gene Therapy Notable 2022 Start-up Companies 
Figure 38: Cell and Gene Therapy Historic & Futuristics Trends of Patent, by Volume, 2018-2027 
Figure 39: Cell and Gene Therapy Patent: Analysis by Type of Cell Therapy Players, 2022 vs 2025 
Figure 40: Cell and Gene Therapy Patent: Analysis by Type of Gene Therapy Players, 2022 vs 2025 
Figure 41: Cell and Gene Therapy Patent: Analysis by Cell Type, 2022 vs 2025 
Figure 42: Cell and Gene Therapy Patent: Analysis by Product, 2022 
Figure 43: Cell Therapy Patent: Analysis by Patent Type, 2018-2022 
Figure 44: Gene Therapy Patent: Analysis by Patent Type, 2018-2022 
Figure 45: Cell Therapy Patent: Analysis by Patent Legal Status, 2018-2022 
Figure 46: Gene Therapy Patent: Analysis by Patent Legal Status, 2018-2022 
Figure 47: Cell Therapy Patent: Analysis by Top Patent Owners, 2022 
Figure 48: Gene Cell Therapy Patent: Analysis by Top Patent Owners, 2022 
Figure 49: Cell Therapy Patent: Analysis by Top Patent Applicants, 2022 
Figure 50: Gene Cell Therapy Patent: Analysis by Top Patent Applicants, 2022 
Figure 51: Cell Therapy Key Patent Applicant: Texas University INC and Their CPC Classification Code  Analysis, 2022 
Figure 52: Cell Therapy Key Patent Applicant: University of California and Their CPC Classification Code  Analysis, 2022 
Figure 53: Cell Therapy Key Patent Applicant: Juno Therapeutics and Their CPC Classification Code  Analysis, 2022 
Figure 54: Cell Therapy Key Patent Applicant: University of Pennsylvania and Their CPC Classification Code  Analysis, 2022 
Figure 55: Cell Therapy Key Patent Applicant: Dana Farber Cancer Inst Inc and Their CPC Classification Code  Analysis, 2022 
Figure 56: Gene Therapy Key Patent Applicant: University of Texas and Their CPC Classification Code  Analysis, 2022 
Figure 57: Gene Therapy Key Patent Applicant: University of California and Their CPC Classification Code  Analysis, 2022 
Figure 58: Gene Therapy Key Patent Applicant: National Institute of Health and Medical Research and Their CPC Classification Code  Analysis, 2022 
Figure 59: Gene Therapy Key Patent Applicant: Research Institute Nationwide Children’s Hospital and Their CPC Classification Code  Analysis, 2022 
Figure 60: Gene Therapy Key Patent Applicant: University of Pennsylvania and Their CPC Classification Code  Analysis, 2022 
Figure 61: Cell Therapy Patent: Analysis by Published Status, 2018-2022 
Figure 62: Gene Therapy Patent: Analysis by Published Status, 2018-2022 
Figure 63: Cell Therapy Patent: Analysis by Investors, 2022 
Figure 64: Gene Therapy Patent: Analysis  by Investors, 2022 
Figure 65: Cell Therapy Patent: Analysis by CPC Classification Code, 2022 
Figure 66: Gene Therapy Patent: Analysis by CPC Classification Code, 2022 
Figure 67: Cell Therapy Patent: Analysis by Documents by Jurisdiction, 2022 
Figure 68: Gene Therapy Patent: Analysis by Documents by Jurisdiction, 2022 
Figure 69: List of Recent Cell Therapy Patents 
Figure 70: List of Recent Cell Therapy Patents 
Figure 71: Cell and Gene Therapy Clinical Trial Historical and Futuristics Trend, by Volume, 2018-2027 
Figure 72: Cell and Gene Therapy Clinical Trial Region-wise Share and Forecast, by Volume (%), 2018-2027 
Figure 73: Cell Therapy Clinical Trial: Analysis by Country-wise 
Figure 74: Gene Therapy Clinical Trial: Analysis by Country-wise 
Figure 75: Cell and Gene Therapy Clinical Trial: Analysis by Age Group 
Figure 76: Cell and Gene Therapy Clinical Trial: Analysis by Funding Agency 
Figure 77: Cell and Gene Therapy Clinical Trial: Analysis by Documents 
Figure 78: Cell and Gene Therapy Clinical Trial: Analysis by Therapeutic Class, by Volume 
Figure 79: Cell and Gene Therapy Clinical Trial: Analysis by Phase-wise 
Figure 80: Cell and Gene Therapy Clinical Trial: Analysis by Status 
Figure 81: Number of Cell and Gene Therapy Assets in Clinical Pipeline 
Figure 82: Share of Cell and Gene Therapy in Pipeline Targeting Rare & Non-Rare Diseases 
Figure 83: Cell and Gene Therapy Clinical Trial: Analysis by Study Type 
Figure 84: Cell and Gene Therapy Companies Competitive Landscape 
Figure 85: Cell and Gene Therapy: Companies by Market Share, 2022 
Figure 86: Cell and Gene Therapy Companies Mapping Quadrant 
Figure 87: Cell and Gene Therapy: Companies by End Users 
Figure 88: Cell and Gene Therapy: Companies by Geography 
Figure 89: Cell and Gene Therapy: Companies by Different Therapy Segment 
Figure 90: Gene Therapy Public Company Competitive Landscape 
Figure 91: Cell Therapy Public Company Competitive Landscape 
Figure 92: Cell Therapy Public Company Competitive Landscape 
Figure 93: Global Cell and Gene Therapy Market Size by Value (USD MM) 2018-2027  
Figure 94: Global Cell and Gene Therapy Market Share by Different Therapy Segment (%), 2018-2027  
Figure 95: Global Cell and Gene Therapy Market Size by Cell and Gene Modified Cell Therapies, by Value (USD MM), 2018-2027  
Figure 96: Global Cell and Gene Therapy Market Size by Gene Therapy and Genome Therapy, by Value (USD MM) 2018-2027  
Figure 97: Global Cell and Gene Therapy Market Size by DNA & RNA Therapeutics, by Value (USD MM) 2018-2027  
Figure 98: Global Cell and Gene Therapy Market Share Purpose of Manufacturing (%), 2018-2027  
Figure 99: Global Cell and Gene Therapy Market Size by Commercial, by Value (USD MM) 2018-2027  
Figure 100: Global Cell and Gene Therapy Market Size, By Clinical, by Value (USD MM) 2018-2027  
Figure 101: Global Cell and Gene Therapy Market Share by Product (%), 2018-2027  
Figure 102: Global Cell and Gene Therapy Market Share by Route of Administration (%), 2018-2027  
Figure 103: Global Cell and Gene Therapy Market Size by Injectables, by Value (USD MM) 2018-2027  
Figure 104: Global Cell and Gene Therapy Market Size by Topicals, by Value (USD MM) 2018-2027  
Figure 105: Global Cell and Gene Therapy Market Size by Infusions, by Value (USD MM) 2018-2027  
Figure 106: Global Cell and Gene Therapy Market Size by Bio scaffolds, by Value (USD MM) 2018-2027  
Figure 107: Global Cell and Gene Therapy Market Share by Type of Diseases (%), 2018-2027  
Figure 108: Global Cell and Gene Therapy Market Share by Rare Diseases, by Value (UDS MM) 2018-2027  
Figure 109: Global Cell and Gene Therapy Market Share by Non-Rare Diseases, by Value (UDS MM) 2018-2027  
Figure 110: Global Cell and Gene Therapy Market Share by Type of Cell (%), 2018-2027  
Figure 111: Global Cell and Gene Therapy Market Share by CAR-T Cell, by Value (UDS MM) 2018-2027  
Figure 112: Global Cell and Gene Therapy Market Share by TCR Cell, by Value (UDS MM) 2018-2027  
Figure 113: Global Cell and Gene Therapy Market Share by Therapy (%), 2018-2027  
Figure 114: Global Cell and Gene Therapy Market Size by T-Cell Therapies, by Value (USD MM), 2018-2027  
Figure 115: Global Cell and Gene Therapy Market Size by NK Cell, by Value (USD MM), 2018-2027  
Figure 116: Global Cell and Gene Therapy Market Size by Dendritic Cell Therapies, by Value (USD MM), 2018-2027  
Figure 117: Global Cell and Gene Therapy Market Size by Stem Cell Therapies, by Value (USD MM), 2018-2027  
Figure 118: Global Cell and Gene Therapy Market Share by Source of Cell (%), 2018-2027  
Figure 119: Global Cell and Gene Therapy Market Size by Autologous (USD MM), 2018-2027  
Figure 120: Global Cell and Gene Therapy Market Size by Allogenic (USD MM), 2018-2027  
Figure 121: Global Cell and Gene Therapy Market Share by Delivery Mode (%), 2018-2027  
Figure 122: Global Cell and Gene Therapy Market Size by In-vivo, by Value (USD MM), 2018-2027  
Figure 123: Global Cell and Gene Therapy Market Size by Ex-vivo, by Value (USD MM), 2018-2027  
Figure 124: Global Cell and Gene Therapy Market Share by Source of Manufacturing (%), 2018-2027  
Figure 125: Global Cell and Gene Therapy Market Size by In-House, by Value (USD MM), 2018-2027  
Figure 126: Global Cell and Gene Therapy Market Size by Contract Manufacturing, by Value (USD MM), 2018-2027  
Figure 127: Global Cell and Gene Therapy Market Share by Therapeutic Class (%), 2018-2027  
Figure 128: Global Cell and Gene Therapy Market Size by Oncology, by Value (USD MM), 2018-2027  
Figure 129: Global Cell and Gene Therapy Market Size by Neurology, by Value (USD MM), 2018-2027  
Figure 130: Global Cell and Gene Therapy Market Size by Ophthalmology, by Value (USD MM), 2018-2027   
Figure 131: Global Cell and Gene Therapy Market Size by Musculoskeletal, by Value (USD MM), 2018-2027  
Figure 132: Global Cell and Gene Therapy Market Size by Others, by Value (USD MM), 2018-2027  
Figure 133: Global Cell and Gene Therapy Market Share by Technology (%), 2018-2027  
Figure 134: Global Cell and Gene Therapy Market Size by Viral Vector Technology, by Value (USD MM), 2018-2027  
Figure 135: Global Cell and Gene Therapy Market Size by Cell Immortalization Technology, by Value (USD MM), 2018-2027  
Figure 136: Global Cell and Gene Therapy Market Size by Genome Editing Technology, by Value (USD MM), 2018-2027  
Figure 137: Global Cell and Gene Therapy Market Size by Others Technologies, by Value (USD MM), 2018-2027  
Figure 138: Global Cell and Gene Therapy Market Share by End User (%), 2018-2027  
Figure 139: Global Cell and Gene Therapy Market Size by Pharmaceutical & Biotechnology Companies, by Value (USD MM), 2018-2027  
Figure 140: Global Cell and Gene Therapy Market Size by Academic & Research Institutes, by Value (USD MM), 2018-2027  
Figure 141: Global Cell and Gene Therapy Market Size by Hospital & Clinics, by Value (USD MM), 2018-2027  
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